SYNERGISTIC EFFECT OF SUBTOXIC-DOSE CISPLATIN AND TRAIL TO MEDIATE APOPTOSIS BY DOWN-REGULATING DECOY RECEPTOR 2 AND UP-REGULATING CASPASE-8, CASPASE-9 AND BAX EXPRESSION ON NCI-H460 AND A549 CELLS

Synergistic Effect of Subtoxic-dose Cisplatin and TRAIL to Mediate Apoptosis by Down-regulating Decoy Receptor 2 and Up-regulating Caspase-8, Caspase-9 and Bax Expression on NCI-H460 and A549 Cells

Objective(s): Although tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can selectively induce apoptosis in tumor cells, more than half of tumors including non-small cell lung cancer (NSCLC) exhibit TRAIL-resistance.The purpose of this study was to determine whether subtoxic-dose cisplatin and TRAIL could synergistically enhance apop

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Green Synthesis of Zinc Oxide Nanoparticles: Fortification for Rice Grain Yield and Nutrients Uptake Enhancement

Applications of metal oxide nanoparticles in the agriculture sector are being extensively included as the materials are considered superior.In the present work, zinc oxide nanoparticle (ZnO NPs), with a developing fertilizer, is applied in the fortification of rice grain yield and nutrient uptake enhancement.To evaluate the role of ZnO NP, two fiel

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Evaluation of in-house loop-mediated isothermal amplification for tuberculosis diagnosis compared with Xpert MTB/RIF

Introduction: To evaluate the diagnostic 75 corvette door panels performances of an in-house loop-mediated isothermal amplification (LAMP) kit and the Xpert MTB/RIF test for the diagnosis of pulmonary tuberculosis in a resource-limited setting, this study was performed at the University Teaching Hospital, Ministry of Health, the Republic of Zambia.

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